While non-specific conditioned enlargements result in pyogenic granuloma, some conditioned enlargements of the gingivae happen during pregnancy, puberty, and vitamin C insufficiency. Hormone-based gingival inflammation, which increases the risk of gingival bacterial proliferation, is a common occurrence in pregnant women. Pregnancy-related gingivitis is brought on by dangerous bacteria that proliferate in and out of the periodontal tissues as a result of hormonal changes during pregnancy. Pregnancy's second and third trimesters are often when the inflammatory response is at its highest. There is a systemic-oral connection between oral inflammation and preterm birth or low birth weight. The oral bacterial population increases during pregnancy, providing harmful germs with an ideal environment. Bacteria may enter the bloodstream and travel to the developing fetus as a result of poor oral hygiene, gingivitis, or periodontitis. The bacteria undermine the amniotic sac's sterility when they enter the placenta, increasing the risk of preterm labor. Most childbearing women are aware of the link between maintaining oral health during pregnancy, which could lead to unavoidable difficulties. In light of these facts, dental hygienists should inform pregnant women of the importance of maintaining their oral health. Pregnancy-associated gingivitis and pregnancy-associated pyogenic granuloma are classified as "gingival disease affected by systemic variables" by the International Workshop of Gingival Diseases Most medical professionals don't inform their patients about the significance of oral care during pregnancy. In a study evaluating the knowledge of obstetricians regarding periodontitis as a risk factor for preterm birth or a low birth weight, 49percent of clinical experts suggested dental exams to their patients infrequently or never, even though 84% thought periodontitis was a significant risk factor in pregnancy. Gum disease related with pregnancy affects 50 to 70 percent of women. It may be specific or generic. Between second and eighth months of pregnancy are often when it shows symptoms. The gingiva appears red or swollen, and the gingival borders are rolled. A clinical indicator is bleeding while being gently probed. This is effectively treated with scaling, rigorous oral hygiene instructions from the dental hygienist, and comprehensive daily practices from the patient. It happens when the patient's systemic condition causes their reaction to plaque accumulation to be amplified. In the marginal or connected gingiva, granulomas can appear as a single or many masses during pregnancy. These masses have a mushroom-like appearance, are sessile, easily bleed, and protrude from the edge or interproximal region. The lesions have precise markings but do not progress to the bones.